In silico-aided molecular identification of potential pathogenic and prognostic differentially expressed genes (DEGs) associated with human trypanosomiasis

identification of differentially expressed genes in l02 human hepatocyte induced by hepatitis c virus core protein

Transcriptomic Analysis Identifies Differentially Expressed Genes (DEGs) Associated with Bolting and Flowering in Radish (Raphanus sativus L.)

The transition of vegetative growth to bolting and flowering is an important process in the life cycle of plants, which is determined by numerous genes forming an intricate network of bolting and flowering. However, no comprehensive identification and profiling of bolting and flowering-related genes have been carried out in radish. In this study, RNA-Seq technology was applied to analyze the di...

Molecular identification of Brucella species and biovars associated with animal and human infection in Iran

Brucellosis is a costly contagious disease of human, domestic and wild animals. It is a serious health problem in Iran causing significant economic losses therefore, control approaches to prevent its spread are of great importance. In Iran, the species and biovars of virulent Brucella species are still under-reported due to the inadequate diagnostic protocols and insufficient laborator...

Rough sets for in silico identification of differentially expressed miRNAs

The microRNAs, also known as miRNAs, are the class of small noncoding RNAs. They repress the expression of a gene posttranscriptionally. In effect, they regulate expression of a gene or protein. It has been observed that they play an important role in various cellular processes and thus help in carrying out normal functioning of a cell. However, dysregulation of miRNAs is found to be a major ca...

In silico Analysis of Transcription Factors Associated to Differentially Expressed Genes in Irradiated Glioblastoma Cell Lines

Glioblastoma multiforme (GBM) is one of the most frequent tumors in the central nervous system and the most malignant tumor among gliomas. In the past two decades, cytogenetic and molecular genetic studies have identified a number of recurrent chromosomal abnor‐ malities and genetic alterations in malignant gliomas, particularly in GBM [1]. It was already described that GBM harbors combinations...